| EN

曹彬2023.jpg

曹彬

联系方式:caobin@cpl.ac.cn

caobin_ben@163.com


教育经历


1996-1998 中国协和医科大学(七转八年制),博士

1990-1996 山东医科大学(七年制)


工作经历


2020-至今      昌平实验室,领衔科学家

2018-至今      清华大学-北京大学生命科学联合中心, 教授

2015-至今      中日友好医院呼吸与危重症医学科,历任科主任、副院长

2006-2015年 首都医科大学附属北京朝阳医院感染和临床微生物科,主任医师

1998-2006    北京协和医院呼吸内科,主治医师


研究简介


长期致力于急性呼吸道感染及新发突发呼吸道传染病关键科学问题的研究,研究主要研究方向为病毒性肺炎和病毒性感染中毒症(viral sepsis)的感染免疫,在流感病毒、腺病毒、支原体和耐药细菌所致呼吸感染的流行病学、病原学、免疫学机制和临床救治领域取得了具有国际影响的创新性成果,研究结果纳入多个国内外临床治疗指南。9项研究成果发表在NEJM,Lancet等顶级杂志。主要研究领域包括:

1. 病毒性肺炎的流行病学、临床特点

2. 流感病毒感染的致病机制,病毒性感染中毒症的发生机制

3. 耐药呼吸道病原体感染的诊断、治疗及耐药机制


主要荣誉


2021 华夏医学科技奖

2020 上海市科学技术奖一等奖

2020 全国抗击新冠肺炎疫情先进个人

2020 全国创新争先奖

2018 杰出呼吸学术贡献奖

2017 国家科学技术进步奖特等奖

2016 中华预防医学会科学技术奖一等奖

2014 吴阶平-保罗·杨森医学药学奖

2011 北京市科学技术奖一等奖等


代表性成果


1.Lixue Huang, Xia Li, Xiaoying Gu , Hui Zhang, LiLi Ren, Li Guo, Min Liu, Yimin Wang, Dan Cui, Yeming Wang, Xueyang Zhang, Lianhan Shang, Jingchuan Zhong, Xinming Wang, Jianwei Wang* , Bin Cao*.Health outcomes in people 2 years after surviving hospitalisation with COVID-19: a longitudinal cohort study. Lancet Respir Med. 2022 May 11; S2213-2600(22)00126-6.


2.Lixue Huang, Qun Yao, Xiaoying Gu, Qiongya Wang, Lili Ren, Yeming Wang, Ping Hu, Li Guo, Min Liu, Jiuyang Xu, Xueyang Zhang, Yali Qu, Yanqing Fan, Xia Li, Caihong Li, Ting Yu, Jiaan Xia, Ming Wei, Li Chen, Yanping Li, Fan Xiao, Dan Liu, Jianwei Wang*, Xianguang Wang*, Bin Cao*. 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study. Lancet, 398(10302), 747-758 (2021)


3.Chaolin Huang, Yeming Wang, Xingwang Li, Lili Ren Jianping Zhao, Yi Hu, Li Zhang, Guohui Fan, Jiuyang Xu, Xiaoying Gu, Zhenshun Cheng, Ting Yu, Jiaan Xia, Yuan Wei, Wenjuan Wu, Xuelei Xie, Wen Yin, Hui Li, Min Liu, Yan Xiao, Hong Gao, Li Guo, Jungang Xie, Guangfa Wang, Rongmeng Jiang, Zhancheng Gao, Qi Jin, Jianwei Wang*, Bin Cao*. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet, 2020, 395(10223): 497-506


4.Fei Zhou, Ting Yu, Ronghui Du, Guohui Fan, Ying Liu, Zhibo Liu, Jie Xiang, Yeming Wang, Bin Song, Xiaoying Gu, Lulu Guan, Yuan Wei, Hui Li, Xudong Wu, Jiuyang Xu, Shengjin Tu, Yi Zhang, Hua Chen*, Bin Cao*. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet, 2020, 395(10229): 1054-1062


5.Hui Li, Liang Liu, Dingyu Zhang, Jiuyang Xu, Huaping Dai, Nan Tang, Xiao Su, Bin Cao. SARS-CoV-2 and viral sepsis: observations and hypotheses. Lancet, 2020, 395(10235): 1517-1520


6. Bin Cao*, Yeming Wang, Danning Wen, Wen Liu, Jingli Wang, Guohui Fan, Lianguo Ruan, Bin Song, Yanping Cai, Ming Wei, Xingwang Li, Jiaan Xia, Nanshan Chen, Jie Xiang, Ting Yu, Tao Bai, Xuelei Xie, Li Zhan, Caihong Li, Ye Yuan, Hua Chen, Huadong Li, Hanping Huang, Shengjing Tu, Fengyun Gong, Ying Liu, Yuan Wei, Chongya Dong, Fei Zhou, Xiaoying Gu, Jiuyang Xu, Zhibo Liu, Yi Zhang, Hui Li, Lianhan Shang, Ke Wang, Kunxia Li, Xia Zhou, Xuan Dong, Zhaohui Qu, Sixia Lu, Xujuan Hu, Shunan Ruan, Shanshan Luo, Jing Wu, Lu Peng, Fang Cheng, Lihong Pan, Jun Zou, Chunmin Jia, Juan Wang, Xia Liu, Shuzhen Wang, Xudong Wu, Qin Ge, Jing He, Haiyan Zhan, Fang Qiu, Li Guo, Chaolin Huang, Thomas Jaki, Frederick G Hayden, Peter W Horby, Dingyu Zhang*, Chen Wang*. A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19. N Engl J Med, 2020, 382(19): 1787-1799


7.eming Wang, Dingyu Zhang, Guanhua Du, Ronghui Du, Jianping Zhao, Yang Jin, Shouzhi, Ling Gao, Zhenshun Cheng, Qiaofa Lu, Yi Hu, Guangwei Luo, Ke Wang, Yang Lu, Huadong Li, Shuzhen Wang, Shunan Ruan, Chengqing Yang, Chunlin Mei, Yi Wang, Dan Ding, Feng Wu, Xin Tang, Xianzhi Ye, Yingchun Ye, Bing Liu, Jie Yang, Wen Yin, Aili Wang, Guohui Fan, Fei Zhou, Zhibo Liu, Xiaoying Gu, Jiuyang Xu, Lianhan Shang, Yi Zhang, Lianjun Cao, Tingting Guo, Yan Wan, Hong Qin, Yushen Jiang, Thomas Jaki, Frederick G Hayden, Peter W Horby, Bin Cao*, Chen Wang*. Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial. Lancet, 2020, 395(10236): 1569-1578


8.Xuehong Jia, Bo Liu, Linlin Bao, Qi Lv, Fengdi Li, Hui Li, Yunqing An, Xulong Zhang*, Bin Cao*, Chen Wang*. Delayed oseltamivir plus sirolimus treatment attenuates H1N1 virus-induced severe lung injury correlated with repressed NLRP3 inflammasome activation and inflammatory cell infiltration. PLoS Pathog, 2018, 14(11): e1007428


9.Hui Li, Konrad C Bradley, Jason S Long, Rebecca Frise, Jonathan W Ashcroft, Lorian C Hartgroves, Holly Shelton, Spyridon Makris, Cecilia Johansson, Bin Cao*, Wendy S Barclay*. Internal genes of a highly pathogenic H5N1 influenza virus determine high viral replication in myeloid cells and severe outcome of infection in mice. PLoS Pathog, 2018, 14(1): e1006821


10.Bin Cao,* Xing-Wang Li*, Yu Mao*, Jian Wang*, Hong-Zhou Lu*, Yu-Sheng Chen*, Zong-An Liang*, Lirong Liang, Su-Juan Zhang, Bin Zhang, Li Gu, Lian-He Lu, Da-Yan Wang, Chen Wang; National Influenza A Pandemic (H1N1) 2009 Clinical Investigation Group of China. Clinical features of the initial cases of 2009 pandemic influenza A (H1N1) virus infection in China. N Engl J Med, 2009, 361(26): 2507-2517