教育经历
2002-2007 中国科学院精密测量科学与技术创新研究院,理学博士
1998-2002 武汉大学,物理学,人才基地班,学士
工作经历
2023-现今 昌平实验室
2015-2022 武汉光电国家研究中心生物医学光子学研究部,教授、博士生导师
2008-2015 美国 Purdue 大学物理系、化学系、生物医学工程系,博士后
2007-2008 中国科学院精密测量科学与技术创新研究院,助理研究员
研究简介
王平教授团队紧密结合超快飞秒光学和分子生物学,在生物成像原理与技术上不断探索,于2018年在细胞和组织水平成功获得了110nm分辨的受激拉曼图像。王平教授团队进一步结合医学临床需求,对癌症和肿瘤代谢分子进行化学甄别和成像。在超快领域,王平教授团队应用双飞秒激光技术顺利研制成功2000幅/秒超快分子成像显微镜。近10年来以第一作者或通讯作者在国际一流期刊Nature旗下Light: Science & Applications,Nature Communications, Angew. Chem. Int. Ed. , Advanced Sciences, JACS, Optica, Nano Letters, Small,共发表10多篇代表性高水平论文,总引用超过3000次(Google Scholar)。目前为Nature Methods, Nature Chemical Biology, Nature Communications等重要期刊审稿人。
主要荣誉
获得美国发明专利授权 1 项,中国发明专利授权 5 项,PCT 国际专利 2 项
获得美国普度大学 BME Geddes-Laufman-Greatbatch Award(2013)
代表性成果
1. Y. Bi#, C. Yang#, Y. Chen, S. Yan, G. Yang, Y. Wu, G. Zhang* and P. Wang*. Near-resonance enhanced label-free stimulated Raman scattering microscopy with spatial resolution near 130 nm. Light: science & applications 7, 81 (2018)
2. B. Huang#, S. Yan#, L. Xiao, R. Ji, L. Yang, A. J. Miao* and P. Wang*. Label-Free Imaging of Nanoparticle Uptake Competition in Single Cells by Hyperspectral Stimulated Raman Scattering. Small 14, (2018)
3. H. Li, Y. Cheng, H. Tang, Y. Bi, Y. Chen, G. Yang, S. Guo, S. Tian, J. Liao, X. Lv, S. Zeng, M. Zhu, C. Xu, J. Cheng* and P. Wang*. Imaging Chemical Kinetics of Radical Polymerization with an Ultrafast Raman Microscope. Advanced Science 7, 1903644 (2020)
4. Y. Bi#, C. Yang#, L. Tong#, et al., W. Bao*, L. Ye* and P. Wang*. Far-field transient absorption nanoscopy with sub-50 nm optical super-resolution. Optica 10, 1402 (2020)
5. S. Tian, et al, F. Meng*, J. Lauher*, P. Wang* and Liang Luo*. Polydiacetylene-based Ultrastrong Bioorthogonal Raman Probes for Targeted Live-cell Raman Imaging. Nature Communications 11, 81 (2020)
6. C. Yang#, Y. Bi#, E. Cai, Y. Chen, S. Huang, Z. Zhang, and P. Wang*. Pulse-Sheet Chemical Tomography by Counterpropagating Stimulated Raman Scattering. Optica 8, 3 (2021)
7. G. Yang#, C. Yang#, et al, Y. Wang*, J. Xia* and P. Wang*. Direct Imaging of Integrated Circuits in CPU with 60 nm Super-Resolution Optical Microscope. Nano Letters 21, 3887 (2021)
8. W. Zhu#, E. Cai#, H. Li#, P. Wang*, A. Shen*, J. Popp* and J. Hu*. Precise Encoding of Triple-bond Raman Scattering of Single Polymer Nanoparticles for Multiplexed Imaging Application. Angew. Chem. Int. Ed. 60, 21846-21852 (2021)
9. Y. Ma#, H. Li#, Z. Gong, S. Yang, P. Wang* and C. Tang*. Nucleobase Clustering Contributes to the Formation and Hollowing of Repeat-Expansion RNA Condensate. J. Am. Chem. Soc. 11, 4716-4720 (2022)
10. J. G. Davis, K. P. Gierszal, P. Wang, D. Ben-Amotz*. Water structural transformation at molecular hydrophobic interfaces. Nature 491, 582-585 (2012)