谢晓亮
联系方式：sunneyxie@cpl.ac.cn
教育经历
1985-1990 美国加利福尼亚大学圣迭戈分校 物理化学博士
1980-1984 北京大学化学学院 学士
工作经历
2020-至今 昌平实验室主任
2019-至今 北京大学理学部主任
2018-至今 北京大学李兆基讲席教授
2010-2022 北京大学生物医学前沿创新中心(BIOPIC)主任
2016-2021 北京未来基因诊断高精尖创新中心(ICG)主任
2009-2018 哈佛大学化学与化学生物学系Mallinckrodt讲席教授
1999-2009 哈佛大学化学与化学生物学系终身教授
1992-1998 美国太平洋西北国家实验室(PNNL)资深科学家、首席科学家
1990-1992 美国芝加哥大学博士后
研究简介
谢晓亮是单分子生物物理化学的奠基人之一、相干拉曼散射显微成像技术和单细胞基因组学的开拓者。其团队发明的全基因组扩增技术，已使超过4000个患有单基因遗传病的家庭成功避免了疾病的后代传递。在抗击新冠疫情过程中，谢晓亮团队成功研制出针对所有新冠病毒变种的广谱中和抗体药物，并已将其授权给相关药企。
主要荣誉
2021 北京市科学技术突出贡献中关村奖
2017 中国科学院院士
2017 求是杰出科学家奖
2016 美国医学科学院院士
2015 美国Albany 生物医学奖
2015 美国化学会Peter Debye 物理化学奖
2012 美国化学会Rochester分部Harrison Howe奖
2012 美国生物物理学会Founders奖
2011 美国科学院院士
2008 美国艺术与科学学院院士
2003 以色列Raymond and Beverly Sackler 物理科学奖
代表性成果
1. Cao, Yunlong; Jian, Fanchong; Wang, Jing; Yu, Yuanling; Song, Weiliang; Yisimayi, Ayijiang; Wang, Jing; An, Ran; Chen, Xiaosu; Zhang, Na; Wang, Yao; Wang, Peng; Zhao, Lijuan; Sun, Haiyan; Yu, Lingling; Yang, Sijie; Xiao, Tianhe; Gu, Qingqing; Shao, Fei; Hao, Xiaohua; Xu, Yanli; Jin, Ronghua; Shen, Zhongyang; Wang, Youchun; Xie, Xiaoliang Sunney "Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution," Nature, DOI: 10.1038/s41586-022-05644-7 (2022)
2. Cao, Yunlong; Wang, Jing; Jian, Fanchong; Xiao, Tianhe; Song, Weiliang; Yasimayi, Ayijiang; Huang, Weijin; Li, Qianqian; Wang, Peng; An, Ran; Wang, Jing; Wang, Yao; Niu, Xiao; Yang, Sijie; Liang, Hui; Sun, Haiyan; Li, Tao; Yu, Yuanling; Cui, Qianqian; Liu, Shuo; Yang, Xiaodong; Du, Shuo; Zhang, Zhiying; Hao, Xiaohua; Shao, Fei; Jin, Ronghua; Wang, Xiangxi; Xiao, Junyu; Wang, Youchun; Xie, Xiaoliang Sunney "Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies," Nature 602, 657-663 DOI: 10.1038/s41586-021-04385-3 (2021)
3. Cao, Yunlong; Su, Bin; Guo, Xianghua; Sun, Wenjie; Deng, Yongqiang; Bao, Linlin; Zhu, Qinyu; Zhang, Xu; Zheng, Yinghui; Geng, Chenyang; Chai, Xiaoran; He, Runsheng; Li, Xiaofeng; Lv, Qi; Zhu, Hua; Deng, Wei; Xu, Yanfeng; Wang, Yanjun; Qiao, Luxin; Tan, Yafang; Song, Liyang; Wang, Guopeng; Du, Xiaoxia; Gao, Ning; Liu, Jiangning; Xiao, Junyu; Su, Xiaodong; Du, Zongmin; Feng, Yingmei; Qin, Chuan; Qin, Chengfeng; Jin, Ronghua; Xie, X. Sunney "Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells," Cell 182(1), 73-84.e16 DOI: 10.1016/j.cell.2020.05.025 (2020)
4. Huang, Lei; Bogale, Berhan; Tang, Yaqiong; Lu, Sijia; Xie, X.Sunney; Racowsky, Catherine "Noninvasive preimplantation genetic testing for aneuploidy in spent medium may be more reliable than trophectoderm biopsy," PNAS 16(208), 14105-14112 DOI: 10.1073/pnas.1907472116 (2019)
5. Tan, Longzhi; Xing, Dong; Chang, Chi-Han; Li, Heng; Xie, X.Sunney "Three-dimensional genome structures of single diploid human cells," Science 43, 924-928 DOI: 10.1126/science.aat5641 (2018)
6. Chen, Chongyi; Xing, Dong; Tan, Longzhi; Li, Heng; Zhou, Guangyu; Huang, Lei; Xie, Xiaoliang S. "Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI)," Science 356, 189-194 DOI: 10.1126/science.aak9787 (2017)
7. Yan, Liying; Huang, Lei; Xu, Liya; Huang, Jin; Ma, Fei; Zhu, Xiaohui; Tang, Yaqiong; Liu, Mingshan; Lian, Ying; Liu, Ping; Li, Rong; Lu, Sijia; Tang, Fuchou; Qiao, Jie; Xie, X. Sunney "Live births after simultaneous avoidance of monogenic diseases and chromosome abnormality by next-generation sequencing with linkage analyses," Proc Natl Acad Sci USA 112(52), 15964-15969 DOI: 10.1073/pnas.1523297113 (2015)
8. Chong, Shasha; Chen, Chongyi; Ge, Hao; Xie, X. Sunney "Mechanism of Transcriptional Bursting in Bacteria," Cell 158(2), 314-326 DOI: 10.1016/j.cell.2014.05.038 (2014)
9. Kim, S.; Brostromer, E.; Xing, D.; Jin, J.; Chong, S.; Ge, H.; Wang, S.; Gu, C.; Yang, L.; Gao, Y. Q.; Su, X.-d.; Sun, Y.; Xie, X. S. "Probing Allostery Through DNA," Science 339(6121), 816-819 DOI: 10.1126/science.1229223 (2013)